[Electrophysiologic study of syncope. Prediction of results]

In order to determine the factors predictive of dysrhythmia or disorders of conduction, 20 variables were analysed retrospectively in 201 patients who had undergone electrophysiological exploration. The electrophysiological abnormalities found to be significant were major sinus dysfunction (corrected post-stimulation atrial pause longer than 1 second), subnodal block (HV interval greater than 70 ms) or induction of sustained monomorphous ventricular tachycardia. The electrophysiological exploration gave abnormal results in 50 patients (25 per cent) with ventricular tachycardia in 36, subnodal block in 11 and sinus dysfunction in 5. Multivariate analysis brought out 4 independent variables that were predictive of electrophysiological study results. Presence of a cardiac disease (P less than 0.001), male sex (P less than 0.001), bundle branch block (P = 0.002) or injury consecutive to a syncope (P = 0.003) were associated with an abnormal exploration. The odd ratio of an abnormal electrophysiological exploration in the presence of a variable as compared with the reverse situation was 10, 6.25, 3.8 and 5 respectively. Postprandial syncopes were associated with a negative exploration (P = 0.06). Combining these variables and using a logistic regression model would provide an estimate of the probability of a positive or negative electrophysiological study. The selection of a high probability group would then indicate whether or not an electrophysiological study would be required.