[Electroconvulsion therapy for neuroleptic malignant syndrome]

Area of Science:

• Neuroscience
• Psychiatry
• Pharmacology

Background:

• Recurrent depression requires ongoing management.
• Olanzapine and mirtazapine are common psychotropic medications.
• Neuroleptic Malignant Syndrome (NMS) is a rare but life-threatening adverse drug reaction.

Observation:

• A 64-year-old male patient developed NMS while on olanzapine and mirtazapine.
• Discontinuation of psychotropic drugs and intensive supportive care were initiated.
• Electroconvulsive Therapy (ECT) was administered to the patient.

Findings:

• The patient recovered following the administration of ECT.
• This case highlights the potential efficacy of ECT in managing NMS.
• ECT may be a valuable therapeutic option for refractory NMS.

Implications:

• ECT could be considered in the treatment armamentarium for NMS.
• Further research is warranted to establish the role of ECT in NMS management.
• Understanding NMS treatment is crucial for patient safety in psychopharmacology.