Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tumor Progression02:07

Tumor Progression

6.1K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.1K
Tumor Progression02:07

Tumor Progression

3.1K
3.1K
Cancer02:18

Cancer

51.3K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
51.3K
Tumor Immunotherapy01:27

Tumor Immunotherapy

2.5K
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
2.5K
The Tumor Microenvironment02:17

The Tumor Microenvironment

2.6K
2.6K
The Tumor Microenvironment02:17

The Tumor Microenvironment

6.3K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-throughput screening for novel drug combinations using patient-derived organoids.

Biochemical pharmacology·2026
Same author

High-throughput screening identifies NT-1 that synergizes with MRTX1133 against acquired resistant KRAS<sup>G12D</sup> colorectal cancer.

NPJ precision oncology·2026
Same author

Artificial Intelligence Chatbots and Their Responses to Most Searched Spanish Cancer Questions.

Cancer medicine·2025
Same author

Phase 1 clinical trial of the ataxia telangiectasia and Rad3-related inhibitor berzosertib with irinotecan in patients with advanced solid tumors (ETCTN 9938).

Cancer·2025
Same author

Targeting YES1 enhances the efficacy of chemotherapy, targeted therapy and onco-immunotherapy.

Cellular signalling·2025
Same author

Cyclin-dependent kinase 9 inhibitors as oncogene signaling modulators in combination with targeted therapy for the treatment of colorectal cancer.

bioRxiv : the preprint server for biology·2025

Related Experiment Video

Updated: Apr 23, 2026

Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence
07:54

Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence

Published on: October 25, 2011

20.3K

Tumor heterogeneity and implications for clinical practice

Edward Chu

    Oncology (Williston Park, N.Y.)
    |September 17, 2014
    PubMed
    Summary

    No abstract available in PubMed .

    More Related Videos

    Comparative Lesions Analysis Through a Targeted Sequencing Approach
    08:16

    Comparative Lesions Analysis Through a Targeted Sequencing Approach

    Published on: November 5, 2019

    6.2K
    Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking
    07:34

    Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

    Published on: November 17, 2023

    1.5K

    Related Experiment Videos

    Last Updated: Apr 23, 2026

    Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence
    07:54

    Heterogeneity Mapping of Protein Expression in Tumors using Quantitative Immunofluorescence

    Published on: October 25, 2011

    20.3K
    Comparative Lesions Analysis Through a Targeted Sequencing Approach
    08:16

    Comparative Lesions Analysis Through a Targeted Sequencing Approach

    Published on: November 5, 2019

    6.2K
    Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking
    07:34

    Author Spotlight: Advancing Prostate Cancer Research Through Improved Tissue Sampling and Biobanking

    Published on: November 17, 2023

    1.5K