Related Experiment Video

Updated: Apr 23, 2026

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
03:47

Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography

Published on: November 1, 2024

468

Chronic hives associated with Helicobacter pylori in a child

Anjum Saeed, Asaad Assiri, Abdulrehman Alnimri

    Journal of Ayub Medical College, Abbottabad : JAMC
    |September 18, 2014
    PubMed

    Insights

    Helicobacter pylori (H. pylori) infection can cause chronic urticaria in children when standard treatments fail. Eradicating H. pylori effectively resolved chronic urticaria in a pediatric case, suggesting its consideration in difficult cases.

    Area of Science:

    • Pediatric Gastroenterology
    • Dermatology
    • Infectious Diseases

    Background:

    • Chronic urticaria is a common pediatric condition often requiring complex management strategies.
    • Identifying underlying causes is crucial when conventional therapies prove ineffective.

    Observation:

    • A 9-year-old girl presented with chronic urticaria and suspected celiac disease.
    • Endoscopy revealed H. pylori gastritis; small bowel mucosa was normal.

    Findings:

    • Biopsy confirmed H. pylori gastritis.
    • Successful H. pylori eradication therapy led to complete resolution of chronic urticaria.

    Implications:

    • H. pylori should be considered in the differential diagnosis of pediatric chronic urticaria unresponsive to standard treatments.
    • This case highlights the potential gastrointestinal origins of seemingly dermatological conditions in children.

    More Related Videos

    Author Spotlight: Detection and Treatment of Helicobacter pylori Infection06:40

    Author Spotlight: Detection and Treatment of Helicobacter pylori Infection

    Published on: July 28, 2023

    4.5K
    Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance05:23

    Gastric Mucosa Quantitative Polymerase Chain Reaction Analysis for Detecting Helicobacter pylori and Antibiotic Resistance

    Published on: March 7, 2025

    881

    Related Concept Videos

    Peptic Ulcer01:27

    Peptic Ulcer

    Peptic ulcers are erosive lesions of the gastric or duodenal lining, most commonly caused by Helicobacter pylori infection. This Gram-negative, helical bacterium has adapted to survive the stomach’s acidic environment by producing urease, which converts urea into ammonia and carbon dioxide. The ammonia neutralizes gastric acid in the bacterium’s immediate environment, allowing colonization of the gastric mucosa. H. pylori attaches to mucus-secreting epithelial cells, penetrates the...
    43
    Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy01:16

    Treating Helicobacter pylori in Peptic Ulcers: Antimicrobial Therapy

    Helicobacter pylori, a resilient gram-negative bacterium, can thrive in the stomach's harsh, acidic environment. Infection with H. pylori leads to a cascade of events within the stomach lining. One of the critical disruptions caused by this bacterium is the interference with somatostatin production, a hormone responsible for regulating acid secretion. This interference tips the balance, escalating acid secretion and diminishing bicarbonate levels. This imbalance compromises the defensive...
    2.4K
    Gastritis II: Pathophysiology01:26

    Gastritis II: Pathophysiology

    The pathophysiology of gastritis begins with the colonization of the stomach lining by Helicobacter pylori (H. pylori). This bacterium spreads mainly via the oral-oral route through saliva or shared utensils, and can also be transmitted in overcrowded or unhygienic environments through contaminated water, despite its brief survival outside the body.ColonizationOnce ingested, H. pylori enters the stomach and begins colonization by navigating through the mucus layer lining the stomach wall. It...
    33
    Peptic Ulcer Disease I: Introduction01:30

    Peptic Ulcer Disease I: Introduction

    Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
    An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
    Peptic ulcers can also be...
    1.2K
    Peptic Ulcer Disease I: Introduction01:25

    Peptic Ulcer Disease I: Introduction

    Peptic ulcer disease (PUD) involves breaks in the gastrointestinal tract's mucosal lining, primarily in the stomach and duodenum, with less frequent occurrences in the lower esophagus or near the pylorus.Ulcers can be acute or chronic. Acute ulcers are short-lived with minimal inflammation and heal quickly after the irritant is removed. Chronic ulcers persist, may recur, and often cause scarring due to ongoing tissue damage. Superficial erosions affect only the mucosal layer and are called...
    21
    Peptic Ulcer Disease II: Pathophysiology01:24

    Peptic Ulcer Disease II: Pathophysiology

    Peptic ulcer disease develops when protective mechanisms of the gastrointestinal mucosa are overwhelmed by harmful factors, leading to localized erosions in the stomach or proximal duodenum. The main causes are Helicobacter pylori infection and chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs).Helicobacter pylori–Induced InjuryBacterial Adaptation and Colonization:H. pylori is a spiral, Gram-negative bacterium adapted to the acidic stomach. and transmitted through oral-oral or...
    36