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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
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Papillary Dermis01:11

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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

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Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
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Hypersensitivity Reactions: Delayed Hypersensitivity Reactions01:29

Hypersensitivity Reactions: Delayed Hypersensitivity Reactions

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Delayed-Type Hypersensitivity (DTH), or Type IV hypersensitivity, is a cell-mediated immune response. It occurs when T cells, rather than antibodies, mediate a reaction to specific antigens. It is characterized by a delayed onset (1-2 days) and involves the recruitment of macrophages to the inflammation site.The initiation of a DTH response begins with the sensitization of T cells. During this phase, which lasts at least 1-2 weeks, antigen-specific T cells are activated, clonally expanded, and...
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Hand hygiene01:23

Hand hygiene

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Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
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Reticular Dermis01:15

Reticular Dermis

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The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
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Recognition of Epidermal Transglutaminase by IgA and Tissue Transglutaminase 2 Antibodies in a Rare Case of Rhesus Dermatitis
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Hand dermatitis: an allergist's nightmare.

Lindsey Wold1, Jennifer K Chen, Heather P Lampel

  • 1Chicago Medical School, Rosalind Franklin University of Medicine and Science, 3333 Green Bay Road, North Chicago, IL, 60064, USA, Lindsey.wold@my.rfums.org.

Current Allergy and Asthma Reports
|September 18, 2014
PubMed
Summary
This summary is machine-generated.

Hand dermatitis, a common skin issue, presents diagnostic and treatment challenges due to multifactorial causes. This guide offers allergists a toolkit for managing hand eczema effectively.

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Area of Science:

  • Dermatology
  • Allergology
  • Immunology

Background:

  • Hand dermatitis is a prevalent dermatological condition.
  • Hands frequently encounter allergens and irritants, contributing to dermatitis.
  • Diagnosis and management can be complex due to multifactorial etiologies.

Purpose of the Study:

  • To provide allergists with a practical toolkit.
  • To streamline the diagnosis and management of hand dermatitis.
  • To address the challenges in differentiating causes of hand eczema.

Main Methods:

  • Comprehensive history taking.
  • Focused physical examination.
  • Differential diagnosis of hand dermatitis.

Main Results:

  • Identification of key diagnostic factors.
  • Outline of current and emerging treatment options.
  • Emphasis on the multifactorial nature of hand dermatitis.

Conclusions:

  • A structured approach is crucial for effective hand dermatitis management.
  • Allergists can benefit from a streamlined diagnostic and therapeutic toolkit.
  • Understanding contributing factors aids in successful patient outcomes.