Acute otitis media in children
Roderick P Venekamp1, Roger A M J Damoiseaux, Anne G M Schilder
1Department of Otorhinolaryngology and Julius Centre for Health Sciences and Primary Care, University Medical Centre, Utrecht, The Netherlands.
Insights
This systematic review examines treatments for acute otitis media (AOM) in children. Evidence supports analgesics and judicious antibiotic use for AOM, with myringotomy as an option.
Area of Science:
- Pediatrics
- Otolaryngology
- Evidence-Based Medicine
Background:
- Acute otitis media (AOM) is a frequent pediatric primary care diagnosis.
- Optimal AOM treatment remains a subject of clinical discussion.
Purpose of the Study:
- To systematically review the efficacy and safety of various treatments for AOM in children.
- To address clinical questions regarding analgesics, antibiotics, and myringotomy for AOM.
Main Methods:
- Systematic literature review including Medline, Embase, and Cochrane Library searches up to October 2013.
- Inclusion of 17 studies meeting predefined criteria.
- GRADE evaluation of evidence quality for interventions and inclusion of safety alerts.
Main Results:
- The review synthesizes data on the effectiveness of analgesics, immediate vs. delayed antibiotic prescriptions, and different antibiotic course lengths.
- Information on the role of myringotomy in AOM management is presented.
- The quality of evidence for each intervention was assessed using the GRADE framework.
Conclusions:
- The systematic review provides comprehensive information on the effectiveness and safety of key AOM interventions.
- Findings guide clinical decision-making for pediatric acute otitis media management.
- Highlights the importance of considering evidence quality in treatment selection.
Introduction:
Acute otitis media (AOM) is a common reason for primary care visits in children. Yet, there is considerable debate on the most effective treatment.
Methods And Outcomes:
We conducted a systematic review and aimed to answer the following clinical questions: What are the effects of treatments (analgesics, antibiotics, and myringotomy) in children with AOM? We searched: Medline, Embase, The Cochrane Library, and other important databases up to October 2013 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA).
Results:
We found 17 studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions.
Conclusions:
In this systematic review we present information relating to the effectiveness and safety of the following interventions: analgesics, antibiotics, delayed antibiotics, immediate antibiotics, longer courses of antibiotics, and myringotomy.
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