Related Experiment Video
Updated: Apr 23, 2026

Induction and Assessment of Exertional Skeletal Muscle Damage in Humans
Published on: December 11, 2016
Acute effects of static active or dynamic active stretching on eccentric-exercise-induced hamstring muscle damage
Che-Hsiu Chen1, Trevor C Chen, Mei-Hwa Jan
1Center for Physical Education, National Dong Hwa University, Hualien, Taiwan.
Static active stretching (SAS) before eccentric exercise may reduce muscle damage symptoms. SAS is recommended over dynamic active stretching (DAS) for improving strength, hamstring range of motion, and reducing muscle damage markers.
Area of Science:
- Sports Medicine
- Exercise Physiology
- Muscle Physiology
Background:
- Eccentric exercise can lead to muscle damage, characterized by pain and reduced function.
- Stretching exercises are often used to improve flexibility and may influence muscle damage.
- The effects of different active stretching protocols on muscle damage markers are not fully understood.
Purpose of the Study:
- To investigate if acute static active stretching (SAS) or dynamic active stretching (DAS) reduces muscle damage after eccentric exercise.
- To compare the effectiveness of SAS and DAS in mitigating exercise-induced muscle damage.
Main Methods:
- A randomized controlled trial involving 36 male students.
- Participants underwent either SAS, DAS, or a control condition before performing strenuous eccentric exercise.
- Measurements included range of motion, muscle strength (maximal voluntary isometric contraction), and muscle damage markers (creatine kinase, myoglobin) over 5 days.
Main Results:
- Both SAS and DAS increased hip flexion range of motion compared to the control group.
- DAS significantly increased passive hamstring stiffness (PHS) more than SAS and control.
- Muscle damage markers were lower in the SAS group compared to both DAS and control groups.
Conclusions:
- Pre-exercise active stretching, particularly SAS, can help attenuate symptoms of muscle damage following eccentric exercise.
- SAS is suggested as a superior stretching protocol over DAS for preserving strength, enhancing hamstring range of motion, and reducing muscle damage markers.
Related Concept Videos
Muscle Stimulation Frequency
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Isotonic and Isometric Muscle Contractions
Isotonic contractions
Isotonic contractions occur when a muscle changes length while...
Somatic Spinal Reflexes
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...
Skeletal Muscle Relaxants: Adverse Effects
Unlike...
Relaxation of Skeletal Muscles
When an action potential reaches the axon terminal, it depolarizes the membrane and opens voltage-gated sodium channels. Sodium ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated calcium channels to open....
Exercise and Muscle Performance
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...

