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[Clinical features and risk factors of co-morbid tic disorder in children with attention deficit hyperactivity
Ke-Ying Zhou1, Zhi-Hui Xiao, Yan-Zhao Chen
1Department of Pediatrics, Shenzhen People's Hospital, Second Medical College of Jinan University, Shenzhen, Guangdong, 518020, China. zhoukeying@163.com.
Insights
In children with attention deficit hyperactivity disorder (ADHD), 13.5% also had tic disorder (TD). Improper family education and infection were identified as key risk factors for this comorbidity.
Area of Science:
- Neurodevelopmental disorders
- Child and adolescent psychiatry
- Clinical psychology
Context:
- Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children.
- Tic disorders (TD) frequently co-occur with ADHD, impacting clinical presentation and management.
- Understanding the risk factors for comorbid TD in ADHD is crucial for effective intervention.
Purpose:
- To investigate the clinical features and identify risk factors associated with comorbid tic disorder (TD) in children diagnosed with attention deficit hyperactivity disorder (ADHD).
Summary:
- This study involved 312 children with ADHD, finding a 13.5% comorbidity rate with TD.
- The combined subtype of ADHD showed a significantly higher TD comorbidity rate (24.1%).
- Independent risk factors identified were improper family education (OR=7.000) and infection (OR=2.564).
Impact:
- Findings highlight the significant prevalence of TD in ADHD and identify key modifiable and non-modifiable risk factors.
- Results underscore the need for early intervention strategies targeting identified risk factors to improve outcomes for children with ADHD and comorbid TD.
- This research contributes to a better understanding of the complex interplay between ADHD and TD, informing clinical practice and future research directions.
Objective:
To study the clinical features and risk factors of co-morbid tic disorder (TD) in children with attention deficit hyperactivity disorder (ADHD).
Methods:
A total of 312 children with ADHD were involved in this study. Subtypes of co-morbid TD, incidences of TD in different subtypes of ADHD (ADHD-I, ADHD-HI and ADHD-C) were observed. Thirteen potential factors influencing the comorbidity rate of TD in ADHD were evaluated by univariate analysis and multiple logistic regression analysis.
Results:
Forty-two of 312 children with ADHD suffered from co-morbid TD (13.5%). Comorbidity rate of TD in children with ADHD-C (24.1%) was significantly higher than in those with ADHD-HI (10.9%) and ADHD-I (8.8%) (P<0.05). There were 21 cases (50.0%) of transient TD, 12 cases (28.6%) of chronic TD, and 9 cases (21.4%) of Tourette syndrome. The univariate analysis revealed 6 factors associated with comorbidity: addiction to mobile phone or computer games, poor eating habits, infection, improper family education, poor relationship between parents and poor relationship with schoolmates. Multiple logistic analysis revealed two independent risk factors for comorbidity: improper family education (OR=7.000, P<0.05) and infection (OR=2.564, P<0.05).
Conclusions:
The incidence of co-morbid TD in children with ADHD is influenced by many factors, and early interventions should be performed based on the main risk factors.
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