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Related Experiment Videos

Trunkloads of viruses.

Philip E Pellett1

  • 1Department of Immunology and Microbiology, Wayne State University School of Medicine, Detroit, Michigan, USA ppellett@med.wayne.edu.

Journal of Virology
|September 19, 2014
PubMed
Summary
This summary is machine-generated.

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Elephant herpesvirus 1 (EEHV1) poses a significant threat to Asian elephants (Elephas maximus), causing mortality in approximately 20% of zoo-born individuals. This virus represents a newly recognized subfamily of herpesviruses, impacting both captive and wild elephant populations.

Area of Science:

  • Veterinary Virology
  • Wildlife Health
  • Conservation Biology

Background:

  • Elephant populations face threats from habitat loss, poaching, and infectious diseases.
  • Elephant endotheliotropic herpesvirus 1 (EEHV1) is a significant cause of mortality in young Asian elephants, particularly in zoological settings.
  • EEHV1 belongs to a newly identified subfamily, Deltaherpesvirinae, within the Herpesviridae family.

Purpose of the Study:

  • To highlight the impact of EEHV1 on Asian elephant populations.
  • To contextualize EEHV1 within the broader classification of herpesviruses.
  • To underscore the importance of understanding viral threats to endangered species.

Main Methods:

  • Phylogenetic analysis of EEHV strains.
  • Review of disease incidence data in captive and wild Asian elephants.

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  • Classification of EEHV within the Herpesviridae family.

    • Main Results:

    • EEHV1 causes disease and mortality in approximately 20% of zoo-born Asian elephants.
    • EEHV1 is one of at least six distinct EEHV types.
    • These EEHV strains form a distinct phylogenetic lineage, representing the Deltaherpesvirinae subfamily.

    Conclusions:

    • EEHV1 is a critical pathogen impacting the survival of Asian elephants.
    • The recognition of the Deltaherpesvirinae subfamily provides new insights into herpesvirus evolution.
    • Further research into EEHV is crucial for developing conservation and management strategies for elephants.