[Acute reversible renal insufficiency during treatment with diclofenac]

The authors, after a brief discussion of the main effects of the prostaglandins on renal blood flow, report a case of acute renal failure following the ingestion of diclofenac. Although there is little doubt that diclofenac is among the safest NSAIDs the Authors consider that caution is still necessary, especially in the treatment of older and dehydrated patients.