Related Experiment Video
Updated: Apr 23, 2026

06:04
Patch Angioplasty in the Rat Aorta or Inferior Vena Cava
Published on: February 27, 2017
10.1K
Initial experiences with the Hemopatch® as a hemostatic agent in zero-ischemia partial nephrectomy.
F Imkamp1, Y Tolkach2, M Wolters3
1Clinic for Urology and Urologic Oncology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany. Imkamp.florian@mh-hannover.de.
World Journal of Urology
|September 21, 2014
Summary
This study shows Hemopatch®, a new hemostatic agent, is safe and effective for controlling bleeding during zero-ischemia laparoscopic partial nephrectomy (LPN) for kidney tumors. It proved reliable in initial patient experiences.
Area of Science:
- Urology
- Surgical Oncology
- Minimally Invasive Surgery
Background:
- Nephron-sparing surgery (NSS) is the standard for resectable renal tumors.
- Laparoscopic partial nephrectomy (LPN) has advanced with improved techniques and hemostatic agents.
- Zero-ischemia techniques minimize renal damage during LPN.
Purpose of the Study:
- To evaluate the initial experience with Hemopatch®, a novel hemostatic agent, in zero-ischemia LPN.
- To assess the safety and efficacy of Hemopatch® in controlling bleeding during LPN.
Main Methods:
- Seven patients with renal masses underwent zero-ischemia LPN.
- Hemopatch® was applied to the tumor resection site after parenchymal suturing.
- Data collected included tumor characteristics, operative details, blood loss, and complications.
Main Results:
- Hemopatch® provided sufficient hemostasis in all seven patients.
- No uncontrolled bleeding or postoperative complications were observed.
- Median operative time was 139 minutes, median blood loss was 325 cc, and median hospitalization was 6 days.
Conclusions:
- Hemopatch® is a feasible and reliable hemostatic agent for zero-ischemia LPN.
- Further studies are needed to confirm its role in NSS.
- Hemopatch® shows promise as a valuable tool in nephron-sparing surgery.
Related Concept Videos
Anticoagulant Drugs: Low-Molecular-Weight Heparins
2.5K
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
2.5K
Introduction to Hemostasis
13.6K
Hemostasis is a complex physiological process that prevents excessive bleeding when a blood vessel is injured. It's crucial for maintaining the integrity of the circulatory system, as it ensures that our blood remains fluid while still within the vascular network and yet clots to prevent blood loss upon vessel injury.
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
The three phases of hemostasis involve many clotting factors present in plasma and several substances released by platelets and injured tissue cells. It is a fast, localized,...
13.6K
Extrinsic and Intrinsic Pathways of Hemostasis
10.6K
Blood clotting or coagulation involves extrinsic and intrinsic pathways, which ultimately merge into the common pathway, forming a fibrin clot.
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which...
The Extrinsic Pathway
The extrinsic pathway of coagulation is typically initiated by tissue damage that exposes blood to tissue factor (TF), a protein released by the damaged tissue cells outside the blood vessels—this interaction with TF triggers biochemical reactions involving specific clotting factors. The key player here is Factor VII, which...
10.6K

