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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
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Pediatric migraine prescription patterns at a large academic hospital

Adriana Johnson1, Jonathan Bickel2, Alyssa Lebel1

  • 1P.A.I.N. Group, Department of Anesthesia, Boston Children's Hospital, Harvard Medical School, Waltham, Massachusetts; Headache Program, Departments of Anesthesia and Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.

Pediatric Neurology
|September 22, 2014
PubMed

Insights

Pediatric migraine treatment varies, with sumatriptan, amitriptyline, and topiramate being common prescriptions. This study analyzes drug patterns in children to inform future clinical trials for migraine management.

Area of Science:

  • Pediatric Neurology
  • Clinical Pharmacology

Background:

  • Limited outcome studies exist for pediatric migraine treatment, leading to varied physician approaches.
  • Prescription patterns for pediatric migraine are not well-documented.

Purpose of the Study:

  • To analyze prescription patterns for migraine treatment in pediatric patients.
  • To identify common drug types, age, and sex distributions in pediatric migraine patients.

Main Methods:

  • Retrospective analysis of 4839 patients aged 2-17 years with migraine at a pediatric hospital over 4 years.
  • Data extracted using the i2b2 query tool.
  • Analysis of prescription data based on drug type, patient age, and sex.

Main Results:

  • The most frequently prescribed medications included sumatriptan, amitriptyline, topiramate, ondansetron, and cyproheptadine.
  • The study population comprised 59% females and 41% males.
  • Prescription patterns were analyzed across different age groups within the pediatric range.

Conclusions:

  • Findings align with recent data on pediatric migraine medication choices.
  • Results support the need for further controlled trials in pediatric migraine treatment.
  • The study provides a basis for future research into effective pediatric migraine therapies.
Abstract

Keywords:
amitriptylinemigrainepediatricpharmacotherapyprescriptionsumatriptan

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