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Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

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A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
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Fractures: Bone Repair01:27

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Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
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The Mammary Glands01:12

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The female breast is a hemispheric projection of variable size positioned anterior to the pectoralis major and serratus anterior muscles. A fascia layer composed of dense, irregular connective tissue connects it to these muscles.
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Bone Formation by Intramembranous Ossification01:29

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Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
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Bone Remodeling01:40

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Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
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Bone Formation by Endochondral Ossification01:24

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Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
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Updated: Apr 23, 2026

A Unique Mouse Model for Quantitative Assessment of Biofilm Formation on Surgical Implants in Subcutaneous Abscess
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Bone formation within a breast abscess.

Gurdeep Singh Mannu1, Farid Ahmed1, Giles Cunnick1

  • 1Department of Breast Surgery, Buckinghamshire NHS Trust, UK.

BMJ Case Reports
|September 24, 2014
PubMed
Summary

This case report details osseous metaplasia, or bone formation, within a breast abscess. This rare finding resolved after surgical excision of the abscess.

Area of Science:

  • Oncology
  • Pathology
  • Surgical Breast Disease

Background:

  • Breast abscesses are typically treated with antibiotics and drainage.
  • Persistent or recurrent breast abscesses may require surgical intervention.
  • Osseous metaplasia is the formation of bone in non-skeletal tissues.

Observation:

  • An 87-year-old woman presented with a persistent, painful right breast lump initially diagnosed as an abscess.
  • Standard treatments including antibiotics and aspiration failed to resolve the lesion.
  • Surgical excision was performed due to the refractory nature of the breast abscess.

Findings:

  • Histopathological examination of the excised breast abscess revealed the presence of osseous metaplasia.
  • This represents the formation of bone tissue within the abscess cavity.

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  • No evidence of malignancy was found in conjunction with the abscess or osseous metaplasia.

    • Implications:

    • Osseous metaplasia is a rare complication of breast abscesses, particularly in the absence of malignancy.
    • Surgical excision can effectively treat breast abscesses with osseous metaplasia.
    • This case expands the understanding of benign breast pathologies and their management.