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Clinical correlates of Hachinski ischemic score and vascular factors in cognitive function of elderly

Youn Ho Kim1, Oh Dae Kwon1

  • 1Daegu Catholic University Medical Center, Department of Neurology, School of Medicine, Catholic University of Daegu, 3056-6 Daemyeong 4-dong, Nam-gu, Daegu 705-718, Republic of Korea.

Biomed Research International
|September 24, 2014
PubMed

Insights

The Hachinski ischemic score (HIS) is associated with vascular factors like hypertension and stroke history, and also predicts cognitive function in elderly individuals. This score aids in assessing vascular burden and cognitive status.

Area of Science:

  • Gerontology and Neurology
  • Vascular Cognitive Impairment Research

Background:

  • Vascular factors significantly impact cognitive function in the elderly population.
  • The Hachinski ischemic score (HIS) is a clinical tool used to differentiate between various causes of cognitive impairment.

Purpose of the Study:

  • To investigate the relationship between the Hachinski ischemic score (HIS) and vascular risk factors in community-dwelling elderly individuals.
  • To examine the association between HIS and cognitive function assessments in the same population.

Main Methods:

  • A cross-sectional study involving 348 elderly participants (aged 65 and over) from a rural community.
  • Data collection included demographic information, medical history (hypertension, stroke, cardiovascular disease, dementia), and neurological examination.
  • The Hachinski ischemic score (HIS) was administered by a neurologist, alongside cognitive function tests (Korean Mini-Mental State Examination, Clinical Dementia Rating).

Main Results:

  • Significant associations were found between HIS and history of hypertension (P = 0.008), history of stroke (P < 0.001), family history of dementia (P = 0.01), and history of cardiac diseases (P = 0.012).
  • Both the Korean Mini-Mental State Examination and the Clinical Dementia Rating (Global and Sum of Boxes) showed significant relationships with HIS.
  • HIS demonstrated a correlation with the burden of vascular factors and the status of cognitive function.

Conclusions:

  • The Hachinski ischemic score (HIS) is associated with key vascular risk factors and cognitive function scales in community-dwelling elderly.
  • HIS may serve as a valuable tool for evaluating the extent of vascular contributions to cognitive impairment and predicting cognitive status in older adults.

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