Posture-Dependent Variability in Wrist Ballistocardiogram-Photoplethysmogram Pulse Transit Time: Implication to...

Toward the ultimate goal of robust cuff-less blood pressure (BP) tracking with wrist wearables against postural changes, the goal of this work was to investigate posture-dependent variability in pulse transit time (PTT) measured with ballistocardiogram (BCG) and photoplethysmogram (PPG) signal pair at the wrist.

BCG and PPG signals were acquired from 25 subjects under the combination of 3 body (standing, sitting, and supine) and 3 arm (vertical in head-to-foot direction, placed on the chest, and holding a shoulder) postures. PTT was computed as the time interval between the BCG J wave and the PPG foot, and the impact of the 9 postures on PTT was analyzed by invoking an array of possible physical mechanisms.

Our work suggests that (i) wrist BCG-PPG PTT is consistent under standing and sitting postures with vertically held arms; and (ii) changes in wrist orientation and height as well as restrictions in body and arm movement may alter wrist BCG-PPG PTT via distortions in the wrist BCG and PPG waveforms. The results indicate that wrist BCG-PPG PTT varies with respect to postures even when BP remains constant.

The potential of cuff-less BP tracking via wrist BCG-PPG PTT demonstrated under standing posture with arms vertically down in the head-to-foot direction may not generalize to other body and arm postures.

Understanding the physical mechanisms responsible for posture-induced BCG-PPG PTT variability may increase the versatility of the wrist BCG for cuff-less BP tracking.