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Related Experiment Video

Updated: Apr 23, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
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Imaging, endoscopy and diagnostic surgery.

Lutz Wünsch1, Michael Buchholz

  • 1Klinik für Kinderchirurgie, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany.

Endocrine Development
|September 24, 2014
PubMed
Summary
This summary is machine-generated.

Imaging techniques like ultrasound and MRI are crucial for diagnosing disorders of sex development (DSD). These methods help visualize internal genitalia and gonads, guiding individualized patient care.

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Area of Science:

  • Reproductive medicine
  • Medical imaging
  • Pediatric endocrinology

Background:

  • Disorders of sex development (DSD) require precise diagnosis for appropriate management.
  • Accurate assessment of internal genitalia and gonads is essential for an individualized treatment approach.

Purpose of the Study:

  • To outline the role of various imaging modalities in the diagnostic work-up of individuals with disorders of sex development.
  • To emphasize the importance of imaging in guiding individualized care for DSD patients.

Main Methods:

  • Ultrasound: First-line imaging to detect uterus and gonads.
  • Magnetic Resonance Imaging (MRI): Detailed visualization of sex duct anatomy, prostate, and pelvic muscles.
  • Laparoscopy: Invasive procedure for gonadal dysgenesis and diagnostic uncertainty.

Main Results:

  • Ultrasound effectively identifies key structures like the uterus and gonads.
  • MRI provides comprehensive anatomical details of the pelvic region and sex ducts.
  • Laparoscopy offers critical insights in complex cases, aiding definitive diagnosis.

Conclusions:

  • Imaging plays a pivotal role in the comprehensive evaluation of DSD.
  • A multimodal imaging approach, including ultrasound, MRI, and potentially laparoscopy, is vital for accurate diagnosis and management planning in DSD.
  • Individualized patient care for DSD is significantly enhanced by detailed anatomical information obtained through imaging.