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Transmission-based Precautions II: Airborne and Protective Environment01:25

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Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
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Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

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Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
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Standard Precaution01:26

Standard Precaution

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Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
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Viral Hepatitis I: Introduction01:28

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Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion...
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Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

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A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
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Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment01:08

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Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...
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Related Experiment Video

Updated: Apr 23, 2026

Multicellular Human Alveolar Model Composed of Epithelial Cells and Primary Immune Cells for Hazard Assessment
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Multicellular Human Alveolar Model Composed of Epithelial Cells and Primary Immune Cells for Hazard Assessment

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Ribavirin: the need for exposure precautions.

Kathy Mooney1, Mary Melvin1, Tracy Douglas1

  • 1Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD.

Clinical Journal of Oncology Nursing
|September 26, 2014
PubMed
Summary
This summary is machine-generated.

This study reviews safe administration of ribavirin (RSV treatment) for hematopoietic stem cell transplant patients. It highlights the need for updated policies and staff education to minimize hazardous drug exposure risks.

Keywords:
hazardous handlingquality improvementstem cell/marrow transplantation

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Area of Science:

  • Pharmacology
  • Hematology
  • Infectious Diseases

Background:

  • Ribavirin is crucial for treating respiratory syncytial virus (RSV) pneumonia in high-risk patients, especially those post-hematopoietic stem cell transplantation (HSCT).
  • Ribavirin is a hazardous drug with potential carcinogenic and teratogenic effects, necessitating strict safety protocols.
  • Limited recent research exists on exposure risks and recommended precautions for healthcare staff administering ribavirin.

Purpose of the Study:

  • To examine ribavirin use in HSCT patients with RSV pneumonia.
  • To explore and address safety considerations for healthcare staff handling ribavirin.
  • To improve knowledge and practices regarding safe ribavirin administration and patient education.

Main Methods:

  • Review of current hospital ribavirin policy by nursing leaders on an HSCT unit.
  • Identification of knowledge gaps concerning ribavirin therapy and safe administration.
  • Implementation of policy revisions and enhanced educational strategies for staff and patients.

Main Results:

  • Identified significant knowledge gaps regarding ribavirin therapy and safe handling.
  • Revised hospital ribavirin policy to enhance safety measures.
  • Increased staff knowledge and improved patient education on ribavirin administration.

Conclusions:

  • Updated policies and education are essential for the safe administration of hazardous drugs like ribavirin in HSCT settings.
  • Proactive nursing leadership can effectively address safety concerns and improve clinical practice.
  • Enhanced safety protocols reduce risks associated with ribavirin exposure for healthcare workers and patients.