Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Analgesia and Pain Management

Analgesia and Pain Management

Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comparison of the welfare of beef cattle in housed and grazing systems: hormones, health, and behaviour.

The Journal of agricultural science·2023

Same author

V-QBA vs. QBA-How Do Video and Live Analysis Compare for Qualitative Behaviour Assessment?

Frontiers in veterinary science·2022

Same author

Serum 25-hydroxyvitamin D concentrations and mortality in dogs with blastomycosis.

Veterinary journal (London, England : 1997)·2021

Same author

'Would it sell more pork?' Pig farmers' perceptions of Real Welfare, the welfare outcome component of their farm assurance scheme.

Animal : an international journal of animal bioscience·2019

Same author

First Report of Downy Mildew of Quinoa Caused by Peronospora farinosa f. sp. chenopodii in Denmark.

Plant disease·2019

Same author

An investigation of mechanical nociceptive thresholds in dogs with hind limb joint pain compared to healthy control dogs.

Veterinary journal (London, England : 1997)·2018

Search research articles

Related Experiment Video

Updated: Apr 23, 2026

Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior

Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior

Published on: June 10, 2013

Identifying behavioural differences in working donkeys in response to analgesic administration.

F H Regan¹, J Hockenhull¹, J C Pritchard^2,3

¹School of Veterinary Sciences, University of Bristol, UK.

Equine Veterinary Journal

|September 27, 2014

Summary

Meloxicam (Metacam) improved alertness and activity in working donkeys, indicating its potential to identify pain behaviors. This helps owners and veterinarians manage donkey welfare effectively.

Keywords:

analgesia behaviour meloxicam pain welfare working donkey

More Related Videos

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Published on: July 29, 2014

Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits

Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits

Published on: February 28, 2025

Related Experiment Videos

Last Updated: Apr 23, 2026

Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior

Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior

Published on: June 10, 2013

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities

Published on: July 29, 2014

Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits

Implantation of Electroencephalogram and Electrocardiogram Telemetry Devices in Neonatal Rabbit Kits

Published on: February 28, 2025

Area of Science:

Veterinary Medicine
Animal Behavior
Pharmacology

Background:

Identifying pain behaviors in working donkeys is crucial for their welfare.
Owners and veterinarians require tools to recognize and manage pain in these animals.

Purpose of the Study:

To identify behaviors associated with pain or its relief in working donkeys.
To evaluate the effects of meloxicam (Metacam) on donkey behavior.

Main Methods:

An observer-blinded, placebo-controlled trial was conducted.
Forty adult male working donkeys received either meloxicam or a placebo.
Behavioral observations (postural and event) were recorded using scan and focal sampling.

Main Results:

Donkeys treated with meloxicam showed increased alertness and activity compared to baseline.
Reduced lying down and dozing behaviors were observed in the meloxicam group.
Increased environmental interaction was noted in donkeys receiving meloxicam.

Conclusions:

Meloxicam administration in working donkeys increased alertness and activity, suggesting its utility in identifying pain-related behaviors.
Behavioral assessment aids in prompt identification of welfare issues and monitoring treatment response in donkeys.
Nonsteroidal anti-inflammatory drugs show potential in managing pain and improving welfare in working donkeys.