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Updated: Apr 23, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

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Substitution-inert trinuclear platinum complexes efficiently condense/aggregate nucleic acids and inhibit enzymatic

Jaroslav Malina1, Nicholas P Farrell, Viktor Brabec

  • 1Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i. Kralovopolska 135, CZ-61265 Brno (Czech Republic) http://www.ibp.cz/en/departments/molecular-biophysics-and-pharmacology/info-about-the-department.

Angewandte Chemie (International Ed. in English)
|September 27, 2014
PubMed

Keywords:
DNA condensationnucleic acidsplatinumtRNAtopoisomerase I

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