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Establishment of the Dual Humanized TK-NOG Mouse Model for HIV-associated Liver Pathogenesis
Published on: September 11, 2019
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A new HCV mouse model on the block
Rajiv G Tawar1, Laurent Mailly1, Thomas F Baumert2
11] Inserm, U1110, Strasbourg, France [2] Université de Strasbourg, Strasbourg, France.
Cell Research
|September 27, 2014
Abstract:
The investigation of virus-induced liver disease and hepatocellular carcinoma needs small animal models modeling hepatitis C virus (HCV) infection and liver disease biology. A recent study published in Cell Research reports a novel mouse model which is permissive for chronic HCV infection and shows chronic liver injury including inflammation, steatosis and fibrosis.

