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Disease-associated polymorphisms in 9p21 are not associated with extreme longevity

Ada Congrains1, Kei Kamide1,2, Nobuyoshi Hirose3

  • 1Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Osaka, Japan.

Geriatrics & Gerontology International
|September 27, 2014
PubMed
Summary

Genetic variants in the 9p21 region are linked to aging-related diseases. However, these specific single-nucleotide polymorphisms (SNPs) do not appear to contribute to the exceptional longevity seen in centenarians.

Keywords:
agingatherosclerosisgenetic predispositionlongevitypolymorphism

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