Top 10 cardiovascular therapies and interventions for the next decade
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1Cardiovascular Institute, Mount Sinai School of Medicine, One Gustave L. Levy Place, PO Box 1030, New York, NY 10029-6574, USA.
Insights
Cardiovascular disease (CVD) is a leading global cause of death, driven by lifestyle changes and risk factors like obesity and diabetes. This article highlights 10 promising advances to shift focus from treatment to promoting cardiovascular health.
Area of Science:
- Cardiology and Public Health
Background:
- Cardiovascular disease (CVD) is the leading cause of global mortality.
- Western lifestyles, poor nutrition, obesity, diabetes, hypertension, and inactivity are increasing CVD risk, particularly in low- and middle-income countries undergoing industrialization and urbanization.
Approach:
- This perspective article identifies and discusses 10 anticipated breakthroughs in cardiovascular therapies and interventions.
- It emphasizes the impact of globalization and socioeconomic factors on cardiovascular risk.
Key Points:
- The global rise in CVD is linked to the adoption of Western lifestyles and associated risk factors.
- Industrialization, urbanization, and globalization accelerate the shift in cardiovascular risk profiles worldwide.
- Advances in understanding CVD are crucial for future therapeutic strategies.
Conclusions:
- The next decade holds potential for significant progress in cardiovascular medicine.
- The focus is shifting towards proactive promotion of global cardiovascular health rather than solely treating established disease.
Abstract:
Cardiovascular disease (CVD) has become the most-common cause of death worldwide. The Western lifestyle does not promote healthy living, and the consequences are most devastating when social inequalities are combined with economic factors and population growth. The expansion of poor nutritional habits, obesity, and associated conditions (such as diabetes mellitus, hypertension, physical inactivity, and advancing age) are major risk factors for developing CVD and are increasing in prevalence. Individuals in low-income and middle-income countries are undergoing a major shift in cardiovascular risk factors as they adopt Western lifestyles, a phenomenon that is hastened by industrialization, urbanization, and globalization. In this Perspectives article, I predict the 10 most-promising advances in cardiovascular therapies and interventions. Our improved understanding of CVD might help us, during the next decade, to achieve a transition from treating complex disease to promoting global cardiovascular health.
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