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Updated: Apr 23, 2026

Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells
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Analysis of Endocytic Uptake and Retrograde Transport to the Trans-Golgi Network Using Functionalized Nanobodies in Cultured Cells

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Renal sulfatides: sphingoid base-dependent localization and region-specific compensation of CerS2-dysfunction

Christian Marsching1, Mariona Rabionet2, Daniel Mathow3

  • 1Center for Applied Research "Applied Biomedical Mass Spectrometry" (ABIMAS), Mannheim, Germany Lipid Pathobiochemistry Group within Department of Cellular and Molecular Pathology German Cancer Research Center (DKFZ), Heidelberg, Germany Institute of Medical Technology, University of Heidelberg and Mannheim University of Applied Sciences, Mannheim, Germany.

Journal of Lipid Research
|October 1, 2014
PubMed
Summary

Kidney sulfatides exhibit diverse structures, with specific types found in distinct regions. CerS2 deficiency impacts sulfatide composition but does not alter urinary pH, suggesting compensatory mechanisms.

Keywords:
ceramide synthase 2cortexelectrospray ionization-mass spectrometrygalactosylceramide I3-sulfateimaging mass spectrometryin source decayknockoutlactosylceramide II3-sulfateliquid chromatographymatrix-assisted laser desorption/ionization-time-of-flightmedullapapillaeserine palmitoyl-coenzyme A transferase small subunitssphingosinetandem mass spectrometry

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