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Updated: Apr 23, 2026
Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury
Published on: August 16, 2019
[On the formation of open skull fractures inflicted by cutting objects]
Abstract:
The objective of the present work was to study the properties of thrusting weapons, the conditions of their action, and the influence on the formation of cranial vault fractures. The lacerated wounds were simulated using an ordinary axe, native skull and isolated cranial vaults, specially designed multilayer polymeric models of bone and other tissues. This approach made it possible to obtain the objective characteristics of a thrusting blow as a medium-speed thrust (7- 20 m/s) with the impact mass commensurate with or exceeding the weight of the affected object. In indispensable condition for such thrust consists of the counteraction of the forces on a hard substrate. The traumatic agent must have the partially limited and maximally convex contact 1 surface (blade) harder than that of the affected object. Moreover, the character of a lacerated fracture strongly depends on the strin-stress properties of the skull.
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