Stigmatisation, Avoidance Behaviour and Difficulties in Coping are Common Among Adult Patients with Vitiligo

Area of Science:

• Dermatology
• Psychology
• Quality of Life Research

Background:

• Vitiligo is a depigmentation disorder affecting patient well-being.
• Stigmatization and psychological distress are common in vitiligo patients.
• Understanding the impact on quality of life (QoL) is crucial for effective management.

Purpose of the Study:

• To investigate the quality of life, coping mechanisms, depression, and stigmatization in vitiligo patients.
• To compare QoL and psychological parameters between vitiligo patients and controls.
• To assess the effect of pro-pseudocatalase PC-KUS treatment on psychological outcomes.

Main Methods:

• Utilized Dermatology Life Quality Index (DLQI), Adjustment to Chronic Skin Disorders Questionnaire (ACS), and Beck Depression Inventory (BDI).
• Included 96 vitiligo patients and 23 controls, with additional questions on stigmatization and stress.
• Assessed changes in QoL, anxiety, depression, and avoidance behaviors post-treatment.

Main Results:

• Vitiligo patients reported higher levels of social anxiety, avoidance, helplessness, and anxious-depressive mood compared to controls.
• Significant stigmatization was reported, with 90% experiencing inquiries and 66.7% avoiding situations or concealing lesions.
• Pro-pseudocatalase PC-KUS treatment improved social anxiety, anxious-depressive mood, and depression.
• Avoidance and concealment behaviors correlated with poorer outcomes across all assessed questionnaires.

Conclusions:

• Vitiligo negatively impacts patients' QoL, leading to significant psychological distress and social challenges.
• Stigmatization is a major concern, influencing patient behavior and psychological well-being.
• Pro-pseudocatalase PC-KUS demonstrates therapeutic potential for improving the psychological health of vitiligo patients.