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Updated: Apr 23, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Endoscopic endonasal transsphenoidal surgery: implementation of an operative and perioperative checklist
Eisha Christian1, Brianna Harris, Bozena Wrobel
1Department of Neurosurgery, Head and Neck Surgery, Keck School of Medicine of University of Southern California, Los Angeles, California.
Abstract:
Endoscopic endonasal surgery relies heavily on specialized operative instrumentation and optimization of endocrinological and other critical adjunctive intraoperative factors. Several studies and worldwide initiatives have previously established that intraoperative and perioperative surgical checklists can minimize the incidence of and prevent adverse events. The aim of this article was to outline some of the most common considerations in the perioperative and intraoperative preparation for endoscopic endonasal transsphenoidal surgery. The authors implemented and prospectively evaluated a customized checklist at their institution in 25 endoscopic endonasal operations for a variety of sellar and skull base pathological entities. Although no major errors were detected, near misses pertaining primarily to missing components of surgical equipment or instruments were identified in 9 cases (36%). The considerations in the checklist provided in this article can serve as a basic template for further customization by centers performing endoscopic endonasal surgery, where their application may reduce the incidence of adverse or preventable errors associated with surgical treatment of sellar and skull base lesions.
Insights
A checklist for endoscopic endonasal surgery preparation helps prevent errors. This study found near misses in 36% of cases, mainly due to missing instruments, highlighting the need for standardized surgical checklists.
Area of Science:
- Neurosurgery
- Otolaryngology
- Endocrinology
Background:
- Endoscopic endonasal surgery requires specialized instruments and optimized intraoperative factors.
- Surgical checklists are proven to minimize adverse events in perioperative and intraoperative settings.
Purpose of the Study:
- To outline perioperative and intraoperative preparation considerations for endoscopic endonasal transsphenoidal surgery.
- To evaluate a customized checklist's effectiveness in reducing errors.
Main Methods:
- A customized checklist was implemented and prospectively evaluated.
- The checklist was used in 25 endoscopic endonasal operations for sellar and skull base pathologies.
Main Results:
- No major errors were detected during the study period.
- Near misses, primarily related to missing surgical equipment or instruments, occurred in 9 cases (36%).
Conclusions:
- The developed checklist can serve as a template for centers performing endoscopic endonasal surgery.
- Implementing such checklists may reduce adverse or preventable errors in treating sellar and skull base lesions.
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