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Updated: Apr 23, 2026

Surgical Bone Implantation Technique for Rat Tibia Models of Diabetes and Osteoporosis
Published on: July 5, 2024
Low-magnitude high-frequency loading, by whole-body vibration, accelerates early implant osseointegration in
Yong-Qiang Liang1, Meng-Chun Qi2, Jiang Xu3
1Department of Stomatology, Chinese PLA General Hospital, Beijing 100853, P.R. China.
Abstract:
Osteoporosis deteriorates jaw bone quality and may compromise early implant osseointegration and early implant loading. The influence of low‑magnitude, high‑frequency (LMHF) vibration on peri‑implant bone healing and implant integration in osteoporotic bones remains poorly understood. LMHF loading via whole‑body vibration (WBV) for 8 weeks has previously been demonstrated to significantly enhance bone‑to‑implant contact, peri‑implant bone fraction and implant mechanical properties in osteoporotic rats. In the present study, LMHF loading by WBV was performed in osteoporotic rats, with a loading duration of 4 weeks during the early stages of bone healing. The results indicated that 4‑week LMHF loading by WBV partly reversed the negative effects of osteoporosis and accelerated early peri‑implant osseointegration in ovariectomized rats.
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