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Related Concept Videos

Healing II: Complications01:24

Healing II: Complications

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Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
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Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Related Experiment Video

Updated: Apr 23, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
07:29

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis

Published on: November 12, 2015

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[Complications after corneal cross-linking].

S Taneri1, S Oehler1

  • 1Zentrum für Refraktive Chirurgie, Augenklinik am St. Franziskus Hospital, Münster.

Klinische Monatsblatter Fur Augenheilkunde
|October 2, 2014
PubMed
Summary

Corneal cross-linking shows high success in treating ectasia but can cause complications like infections and opacifications. Further research is needed to monitor long-term outcomes and rare side effects.

Area of Science:

  • Ophthalmology
  • Corneal Surgery
  • Biomaterials Science

Context:

  • Keratoconus and post-excimer laser ablation ectasia pose significant challenges.
  • Corneal cross-linking (CXL) emerged as a promising treatment to halt ectasia progression.
  • Understanding CXL protocols and complication profiles is crucial for patient management.

Purpose:

  • To evaluate the efficacy and safety of various corneal cross-linking protocols.
  • To compare personal clinical experience with existing literature on CXL complications.
  • To assess the long-term implications and potential risks associated with CXL.

Summary:

  • Retrospective analysis of CXL treatments (2007-2014) using diverse protocols.
  • Observed complications include sterile infiltrates, opacifications, keratitis, and mycotic infection.

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Related Experiment Videos

Last Updated: Apr 23, 2026

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
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Second Harmonic Generation Signals in Rabbit Sclera As a Tool for Evaluation of Therapeutic Tissue Cross-linking TXL for Myopia
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Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
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  • Literature review indicates a low incidence of severe complications like endothelial damage, though neoplasia is noted.

    • Impact:

    • Corneal cross-linking demonstrates a favorable success rate with a low complication profile.
    • Endothelial damage risk appears lower than initially feared.
    • Long-term prospective studies are essential to validate efficacy and monitor rare adverse events, including neoplasia.