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The actin binding protein adseverin regulates osteoclastogenesis

Siavash Hassanpour1, Hongwei Jiang2, Yongqiang Wang1

  • 1Matrix Dynamics Group, Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.

Plos One
|October 3, 2014
PubMed
Summary

Adseverin (Ads) regulates osteoclastogenesis (OCG) by binding actin filaments. Ads is induced by RANK-ligand and is crucial for osteoclast formation, impacting cell differentiation and fusion.

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