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Updated: Feb 1, 2026

Routine Screening Method for Microparticles in Platelet Transfusions
Published on: January 31, 2018
[The prevention of transfusion-associated circulatory overload]
1Pôle anesthésie-réanimations-soins intensifs-blocs opératoires-urgences, CHRU de Brest, université de Bretagne occidentale, boulevard Tanguy-Prigent, 29609 Brest cedex, France.
Abstract:
Hydrostatic pulmonary edema is a frequent and severe complication of blood transfusion. Recent epidemiological studies open the way for a better prevention of Transfusion-Associated Circulatory Overload. Preventive measures rely solely on the medical and nursing staff. Mitigation strategies include a careful identification of patients and conditions at-risk, a single-unit transfusion policy in patients with chronic anemia, the use of slow infusion rates, the careful monitoring of patient vital signs (particularly systemic arterial blood pressure). Peritransfusion IV diuretics use is likely to be helpful, although optimal prescribing patterns have not been defined.
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