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Related Experiment Video

Updated: Apr 23, 2026

Online Transcranial Magnetic Stimulation Protocol for Measuring Cortical Physiology Associated with Response Inhibition
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A cortical rein on the tectum's gain.

Sylvia Schröder1, Matteo Carandini1

  • 1University College London, 11-43 Bath Street, London, EC1V 9EL, UK.

Neuron
|October 4, 2014
PubMed
Summary

The visual cortex precisely controls the superior colliculus (tectum) gain retinotopically. This study reveals visual cortex influences tectal operations without altering its fundamental functions.

Area of Science:

  • Neuroscience
  • Sensory processing
  • Sensorimotor integration

Background:

  • The superior colliculus (tectum) is a primitive sensorimotor hub.
  • Its role in sensorimotor control predates cortical evolution.

Purpose of the Study:

  • To investigate the influence of the visual cortex on the superior colliculus.
  • To determine the nature and specificity of this top-down control.

Main Methods:

  • Retinotopic mapping techniques.
  • Analysis of neural activity in the superior colliculus.
  • Investigating visual cortex modulation of tectal function.

Main Results:

  • The visual cortex exerts precise, retinotopic gain control over the superior colliculus.

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  • This control modulates tectal operations without fundamentally changing them.
  • Conclusions:

    • Visual cortex plays a critical role in refining sensorimotor processing via the superior colliculus.
    • Top-down control from the visual cortex allows for specific modulation of tectal gain.