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Updated: Apr 23, 2026
Micro-Computed Tomography Analysis of the Knee in Aged Dunkin-Hartley Guinea Pigs after Intra Articular Injection
Published on: August 2, 2024
Diagnostic Exercise: Metastatic Calcification in Guinea Pigs
J S Villano1, M K Fann2, C E Suckow2
1Animal Resources Center, University of Texas Medical Branch, Galveston, TX Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, MI jvillano@med.umich.edu.
Abstract:
Seven male Hartley guinea pigs, 3 to 18 months old, died or had to be euthanized because of nonspecific clinical signs unresponsive to supportive treatment. Gross necropsy and histopathology findings in all animals included severe soft tissue calcification affecting the myocardium, kidneys, and occasionally the liver.
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