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Sample Preparation to Bioinformatics Analysis of DNA Methylation: Association Strategy for Obesity and Related Trait Studies
Published on: May 6, 2022
Nutritional influences on epigenetic programming: asthma, allergy, and obesity
Debra J Palmer1, Rae-Chi Huang2, Jeffrey M Craig3
1School of Paediatrics and Child Health, University of Western Australia (M561), Roberts Road, Subiaco, Western Australia 6008, Australia; Members of 'In-FLAME' the International Inflammation Network, World Universities Network (WUN).
Abstract:
Observational studies show consistent links between early-life nutritional exposures as important risk factors for the development of asthma, allergy, and obesity. Reliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also influencing immune and metabolic outcomes. Epigenetics is providing substantial advances in understanding how early-life nutritional exposures can effect disease development. This article summarizes current evidence linking the influence of early-life nutritional exposures on epigenetic regulation with a focus on the disease outcomes of asthma, allergy, and obesity.
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