[Lymphomatoid papulosis resembling ecthyma. A case report]

Area of Science:

• Dermatology
• Oncology
• Immunology

Background:

• Lymphomatoid papulosis is a rare, benign skin condition that can mimic malignant lymphoma.
• Distinguishing lymphomatoid papulosis from cutaneous lymphomas is crucial for appropriate patient management.

Observation:

• A 54-year-old female presented with recurrent, disseminated, red-brown papules that were partly ulcerous.
• The lesions spontaneously resolved within 3-6 weeks.
• Histological examination showed atypical lymphocytes with epidermotropism.

Findings:

• Immunohistological analysis revealed a predominance of helper T-cells (CD4+).
• The diagnosis of lymphomatoid papulosis was established based on clinical and pathological findings.
• No evidence of concurrent malignant lymphoma was detected.

Implications:

• This case highlights the importance of thorough histopathological and immunohistochemical evaluation for accurate diagnosis of lymphomatoid papulosis.
• Early and correct diagnosis prevents unnecessary aggressive treatments for lymphoma.
• Understanding the T-cell subset involved aids in characterizing the condition and monitoring potential evolution.