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A ratiometric fluorescent probe for sensing HOCl based on a coumarin-rhodamine dyad
Yan-Ru Zhang1, Xin-Peng Chen, Jing-Shao
1Institute of Organic Chemistry, School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, P. R. China. bxzhao@sdu.edu.cn.
Chemical Communications (Cambridge, England)
|October 7, 2014
Abstract:
We developed a ratiometric fluorescent probe for sensing HOCl based on coumarin and rhodamine acid that is directly used as a detection moiety. The probe shows high selectivity and sensitivity toward HOCl under best working conditions of myeloperoxidase by which HOCl can be generated from hydrogen peroxide and chloride.
