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Updated: Apr 23, 2026
Self-Assembly of Gamma-Modified Peptide Nucleic Acids into Complex Nanostructures in Organic Solvent Mixtures
Published on: June 26, 2020
Probing the importance of π-stacking interactions in DNA-templated self-assembly of bisfunctionalized guanidinium
Delphine Paolantoni1, Jenifer Rubio-Magnieto, Sonia Cantel
1Institut des Biomolécules Max Mousseron (IBMM), UMR 5247 CNRS-Université Montpellier 1, Université Montpellier 2, ENSCM, Ecole Nationale Supérieure de Chimie de Montpellier, 8 Rue de l'Ecole Normale, 34296 Montpellier cedex 5, France. Sebastien.Ulrich@enscm.fr.
Abstract:
Bisfunctionalized guanidinium compounds displaying aromatic side groups of varying size are shown to self-assemble in aqueous solution with single-stranded DNA through phosphodiester backbone recognition. Competition experiments indicate the importance of π-stacking interactions in the stabilization of these DNA-templated supramolecular self-assemblies.
