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Quantum dot labelling of adenovirus allows highly sensitive single cell flow and imaging cytometry

Morgan R Herod1, Robert G Pineda, Vivien Mautner

  • 1School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, LS2 9JT, UK.

Small (Weinheim an Der Bergstrasse, Germany)
|October 7, 2014
PubMed

Keywords:
adenovirusflow cytometrygene therapyimaging cytometryquantum dots

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The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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