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Updated: Aug 17, 2026

07:33
Intralymphatic Immunotherapy and Vaccination in Mice
Published on: February 2, 2014
Total lymphoid irradiation
1Department of Bone Marrow Transplantation and Immunobiology Research, Hadassah University Hospital, 91120 Jerusalem, Israel.
Immunology Today
|October 8, 2014
Abstract:
The delivery of ionizing radiation to lymph nodes, thymus and spleen while non-lymphoid organs are shielded has profoundly immunosuppressive effects that may have value in transplantation and the treatment of autoimmune disorders. Here Shimon Slavin reviews what is known of the cellular consequences of total lymphoid irradiation in animals and discusses the results of its use in various clinical immunosuppressive treatment regimens.

