Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Complement System01:27

Complement System

10.2K
The complement system is a group of approximately 20 plasma proteins that strengthen the body's defenses against infections through opsonization, inflammation, and cell lysis. Opsonization involves coating pathogens with complement proteins, making them more recognizable and facilitating phagocyte engulfment. Certain complement proteins induce inflammation that attracts immune cells to the site of infection. Cell lysis involves the destruction of pathogens through the formation of a...
10.2K
Diversity of Antigen Receptors01:28

Diversity of Antigen Receptors

2.1K
Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
Before encountering any antigen, lymphocytes express these receptors. On B cells, the antigen receptor is a membrane-bound antibody molecule called BCR; on T cells, it is a T cell receptor or TCR. B and T cell receptors are composed of two...
2.1K
Types of Receptors: Cell Surface Receptors01:28

Types of Receptors: Cell Surface Receptors

22.2K
Cell-surface receptors, also known as transmembrane receptors, are cell surface, membrane-anchored (integral) proteins that bind to external ligand molecules. This type of receptor spans the plasma membrane and performs signal transduction, converting an extracellular signal into an intracellular signal. Ligands that interact with cell-surface receptors do not have to enter the cell that they affect. Cell-surface receptors are also called cell-specific proteins or markers because they are...
22.2K
Receptor-mediated Endocytosis01:38

Receptor-mediated Endocytosis

105.2K
Overview
105.2K
Receptor-mediated Endocytosis01:20

Receptor-mediated Endocytosis

10.2K
Receptor-mediated endocytosis is when bulk amounts of specific molecules are imported into a cell after binding to cell surface receptors. The molecules bound to these receptors are taken into the cell through inward folding of the cell surface membrane, which is eventually pinched off into a vesicle within the cell. Structural proteins, such as clathrin, coat the budding vesicle.
Clathrin-Mediated Endocytosis of LDL
One well-characterized example of receptor-mediated endocytosis is the...
10.2K
Receptor-Mediated Endocytosis01:20

Receptor-Mediated Endocytosis

3.9K
3.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade.

Human molecular genetics·2021
Same author

Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in pre-eclampsia: a genetic and functional study.

BJOG : an international journal of obstetrics and gynaecology·2021
Same author

Complement regulators in human disease: lessons from modern genetics.

Journal of internal medicine·2014
Same author

The 20 faces of the fourth component of complement.

Immunology today·2014
Same author

Human C3b- and C4b-regulatory proteins: a new multi-gene family.

Immunology today·2014
Same author

Separation of self from non-self in the complement system.

Immunology today·2014
Same journal

Foreword.

Immunology today·2020
Same journal

The origin and significance of anti-DNA antibodies.

Immunology today·2014
Same journal

Mutations of class II MHC molecules.

Immunology today·2014
Same journal

Antigen processing at the molecular level.

Immunology today·2014
Same journal

Phenotypically and functionally distinct T-cell subsets in anti-tumor responses.

Immunology today·2014
Same journal

Are MHC class II-restricted cytotoxic T lymphocytes important?

Immunology today·2014
See all related articles

Related Experiment Video

Updated: Apr 22, 2026

Measuring Erythrocyte Complement Receptor 1 Using Flow Cytometry
07:20

Measuring Erythrocyte Complement Receptor 1 Using Flow Cytometry

Published on: May 19, 2020

6.9K

Complement receptor structure and function.

G D Ross1, J P Atkinson2

  • 1Division of Rheumatology-Immunology, University of North Carolina, Chapel Hill, NC 27514, USA.

Immunology Today
|October 8, 2014
PubMed
Summary
This summary is machine-generated.

Membrane complement receptors (CRs) are key cell-bound parts of the complement system. Research on CR structure and function is a major focus in current complement studies.

More Related Videos

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment
07:26

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment

Published on: July 18, 2017

12.3K
Evaluation of the Interplay Between the Complement Protein C1q and Hyaluronic Acid in Promoting Cell Adhesion
06:54

Evaluation of the Interplay Between the Complement Protein C1q and Hyaluronic Acid in Promoting Cell Adhesion

Published on: June 15, 2019

5.2K

Related Experiment Videos

Last Updated: Apr 22, 2026

Measuring Erythrocyte Complement Receptor 1 Using Flow Cytometry
07:20

Measuring Erythrocyte Complement Receptor 1 Using Flow Cytometry

Published on: May 19, 2020

6.9K
High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment
07:26

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment

Published on: July 18, 2017

12.3K
Evaluation of the Interplay Between the Complement Protein C1q and Hyaluronic Acid in Promoting Cell Adhesion
06:54

Evaluation of the Interplay Between the Complement Protein C1q and Hyaluronic Acid in Promoting Cell Adhesion

Published on: June 15, 2019

5.2K

Area of Science:

  • Immunology
  • Cell Biology

Background:

  • Membrane complement receptors (CRs) are crucial cell-bound components of the innate immune system.
  • Understanding CRs is vital for comprehending complement system functions.

Purpose of the Study:

  • To highlight the significance of membrane complement receptors in immunology.
  • To emphasize ongoing research into the structure and function of these receptors.

Main Methods:

  • Literature review of current complement research.
  • Analysis of the role of CRs in cellular processes.

Main Results:

  • CRs are recognized as essential cell-bound elements of the complement cascade.
  • Investigating CR structure and function is a primary objective in complement research.

Conclusions:

  • Membrane complement receptors are integral to the complement system's function.
  • Further research into CRs is critical for advancing immunological understanding.