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Updated: Apr 22, 2026

Isolation of Group 2 Innate Lymphoid Cells from Mouse Nasal Mucosa to Detect the Expression of CD226
Published on: May 10, 2022
Interleukin 2: the molecule and its function
1Central Research and Development Department, Glenolden Laboratory, E.1. du Pont de Nemours and Co., Glenolden, PA 19036, USA.
Abstract:
IL2 plays an essential role in triggering proliferation of activated T cells, a response mediated by interaction of the factor with a high-affinity membrane receptor. IL2 also influences a number of other cellular responses, including natural killer cell activity and antibody secretion. Thus, directly or indirectly, IL2 has the properties of both a growth factor and a differentiation signal. Both IL2 and its receptor have been purified to homogeneity and extensively characterized at the molecular level. In this review, Richard Robb discusses the current biochemical understanding of IL2 and its receptor and new information relating to its role in cellular responses.
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