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Updated: Apr 22, 2026

Using Zebrafish Models of Human Influenza A Virus Infections to Screen Antiviral Drugs and Characterize Host Immune Cell Responses
Published on: January 20, 2017
Controlling influenza epidemics
1Department of Microbiology, John Curtin School of Medical Research, Australian National University, Canberra, A.C.T. 2601, Australia.
Abstract:
Vaccination in most countries against influenza virus epidemics is by administration of either inactivated (non-infectious) whole virus preparations or a preparation which contains isolated viral antigens. There is considerable evidence to indicate that natural infection of humans by influenza virus confers more complete and long-lasting protection against subsequent outbreaks than does vaccination with inactivated whole virus and, presumably, subunit vaccines. This article summarizes recent evidence supporting these epidemiological observations.
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