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Updated: Apr 22, 2026

Analyzing the Functions of Mast Cells In Vivo Using 'Mast Cell Knock-in' Mice
Published on: May 27, 2015
Mast cell differentiation and heterogeneity
A D Befus1, J Bienenstock2, J A Denburg3
1Gastrointestinal Research Group, Department of Microbiology and Infectious Diseases, Health Sciences Centre, University of Calgary, Calgary, Alberta, T2N 4NI, Canada.
Abstract:
Major differences between mast cells from different tissues and species have been known for at least 20 years but have been rigorously studied only recently. A recent meeting focused on the ontogeny and differentiation of mast cells, their functional characteristics and the clinical and biological significance of their heterogeneity.
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