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Updated: Apr 22, 2026

"Phagosome Closure Assay" to Visualize Phagosome Formation in Three Dimensions Using Total Internal Reflection Fluorescent Microscopy TIRFM
Published on: August 26, 2016
Stimulate the phagocytes
1Member of the Department of Comparative and Experimental Pathology, University of Florida, Gainesville, Florida, USA.
Abstract:
Investigators from Canada, several European countries, Israel, the Republic of South Africa and the United States of America met earlier this year∗ to discuss whether or not George Bernard Shaw's exhortation to stimulate the phagocytes' pertains equally to host defense against neoplastic cells and microorganisms. The focus was on macrophage activation for killing these diverse targets, and in particular on four questions. What are the characteristics of the macrophages involved in host defense against tumor cells and microorganisms? How are these cells stimulated? How do they mediate their cytotoxic effects? And do they have therapeutic potential?
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