Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Interactions: Parasitism

Microbial Interactions: Parasitism

Parasitism is a form of microbial interaction in which parasitic microbes exploit a host organism for nutrients and shelter, often at the host's expense. Unlike mutualistic relationships, where both organisms benefit, parasitism benefits only the parasite and harms the host.Classification of ParasitesMicrobial parasites are broadly classified based on their location relative to the host.Ectoparasites remain on the host’s surface, such as the skin or outer tissues, drawing nutrients...

Colonisation of Pathogens

Colonisation of Pathogens

Pathogen colonization of host tissues is a critical step in the development of infectious diseases. Various pathogenic microorganisms, including bacteria, fungi, viruses, and protozoa, have evolved complex strategies to attach to, invade, and persist within host environments. These mechanisms enable pathogens to establish infections, evade immune responses, and resist antimicrobial treatments.Attachment to Host CellsIn bacteria, colonization typically begins with adherence to host epithelial...

Defense Against Bacterial Pathogens

Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...

Cell-mediated Immune Responses

Cell-mediated Immune Responses

Defenses Against Pathogens and Herbivores

Defenses Against Pathogens and Herbivores

Plants present a rich source of nutrients for many organisms, making it a target for herbivores and infectious agents. Plants, though lacking a proper immune system, have developed an array of constitutive and inducible defenses to fend off these attacks.

Immune Response Against Viral Pathogens

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Australian parasitological research: now and in 2000.

Parasitology today (Personal ed.)·2006

Same author

Concomitant infections, parasites and immune responses.

Parasitology·2001

Same author

Elimination of lymphatic filariasis as a public health problem.

Parasitology today (Personal ed.)·2000

Same author

Killing of blood stage Plasmodium vinckei petteri by spleen macrophages through L-arginine dependent mechanism.

The Southeast Asian journal of tropical medicine and public health·1998

Same author

Control of coccidiosis: lessons from other sporozoa.

International journal for parasitology·1998

Same author

Designer vaccines for parasitic diseases.

International journal for parasitology·1997

Same journal

Foreword.

Immunology today·2020

Same journal

The origin and significance of anti-DNA antibodies.

Immunology today·2014

Same journal

Mutations of class II MHC molecules.

Immunology today·2014

Same journal

Antigen processing at the molecular level.

Immunology today·2014

Same journal

Phenotypically and functionally distinct T-cell subsets in anti-tumor responses.

Immunology today·2014

Same journal

Are MHC class II-restricted cytotoxic T lymphocytes important?

Immunology today·2014

See all related articles

Search research articles

Related Experiment Video

Updated: Apr 22, 2026

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Published on: January 12, 2017

How parasites evade the immune response.

¹Department of Zoology, King's College London, London WC2R 2LS, UK.

Immunology Today

|October 8, 2014

Summary

This summary is machine-generated.

Parasitic protozoa and worms cause long-lasting infections, but acquired immunity exists. Parasites evade immune responses, causing immunopathology and hindering vaccine development.

More Related Videos

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus

Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus

Published on: March 28, 2025

Related Experiment Videos

Last Updated: Apr 22, 2026

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Inoculating Anopheles gambiae Mosquitoes with Beads to Induce and Measure the Melanization Immune Response

Published on: January 12, 2017

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production

Published on: March 2, 2014

Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus

Isolation And Dendritic Cell-Uptake of Small Extracellular Vesicles from Echinococcus granulosus

Published on: March 28, 2025

Area of Science:

Immunology
Parasitology
Infectious Diseases

Background:

Parasitic protozoa and worm infections can persist for decades.
Previously, effective immunity against parasites was doubted, but infections in immunosuppressed individuals suggested otherwise.
Acquired immunity is now recognized as common, with parasites actively evading immune responses.

Purpose of the Study:

To explore the immunological basis of how parasites evade the immune response.
To understand the mechanisms behind parasite evasion and its consequences.

Main Methods:

The abstract does not specify methods, but refers to a symposium discussing immunological evasion.
Focus is on conceptual understanding and review of existing knowledge.

Main Results:

Parasites actively evade immune responses, rather than being unaffected by them.
This evasion leads to immunopathology, the primary cause of damage in many parasitic infections.
Parasite evasion mechanisms pose significant challenges for developing effective vaccines.

Conclusions:

Acquired immunity plays a crucial role in controlling parasitic infections.
Parasite evasion strategies are central to understanding both disease pathogenesis and vaccine limitations.
Further research into the immunology of parasite evasion is critical for therapeutic and preventative strategies.