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Updated: Aug 10, 2026

VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma
Published on: December 28, 2015
Molecular cloning lends credence to lymphokine research
1Department of Immunology, St. Thomas' Hospital, London SE1 7EH, UK.
Abstract:
There is no longer any doubt that lymphokines are real. At a recent meeting some major advances in lymphokine research were clear - most notably, the application of molecular cloning techniques which have given credence to lymphokines and provided the necessary homogeneous materials for in-vivo and in-vitro studies. Clarification of the structure and function of some lymphokines has diminished the use of assay-related acronyms to describe ill-defined activities and evidence is accumulating for cascades of lymphokines and synergy between molecules. The emerging picture is exciting but complicated.

