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Updated: Apr 22, 2026

A Microscopic 2,3,5-Triphenyltetrazolium Chloride Assay for Accurate and Reliable Analysis of Myocardial Injury
Published on: November 28, 2025
[Methods for detection of myocardial viability in patients with heart failure]
Thamilini Umaramanan, Bhupendar Tayal, Svend Eggert Jensen
1Nuklearmedicinsk Afdeling, Aalborg Universitetshospital, Hobrovej 18-22, 9000 Aalborg.
Abstract:
Myocardial ischaemia may lead to impaired function of the myocardium. Chronic severe myocardial ischaemia may lead to hibernation, a vegetative state with long-lasting dysfunction of the heart. Hibernation is a potentially reversible condition, which may respond to successful revascularization. If myocardial viability is proven, revascularization of the myocardial territory in question might translate into improved subject prognosis. We present an overview of the existing literature on methods for detection of myocardial viability, and the clinical effects of revascularization.
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