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Functional and morphological changes after macular pucker surgery: an optical coherence tomography and
Martina Santarelli1, Daniele Veritti, Gloria Dal Mas
1Medical and Biological Sciences - Ophthalmology, University of Udine, Udine, Italy.
Summary
Macular pucker surgery improves vision and reduces retinal thickness. Pre-operative visual acuity, retinal thickness, and inner/outer segment integrity predict surgical outcomes.
Area of Science:
- Ophthalmology
- Retinal Surgery
Background:
- Macular pucker, an epiretinal membrane, can impair vision.
- Surgical intervention aims to restore visual function.
Purpose of the Study:
- To examine the correlation between functional and morphological outcomes before and after macular pucker surgery.
- To identify predictors of visual recovery post-surgery.
Main Methods:
- Prospective study of 38 eyes with idiopathic macular pucker.
- 25-gauge vitrectomy with internal limiting membrane peeling was performed.
- Outcomes assessed via best-corrected visual acuity (BCVA), spectral-domain optical coherence tomography (SD-OCT), and microperimetry.
Main Results:
- Significant improvement in BCVA (0.34 logMAR) and reduction in central retinal thickness (CRT, 50 µm) were observed.
- Greater BCVA improvement was linked to worse baseline BCVA, shorter final inner/outer segment (IS/OS) interruption, and thinner final CRT.
- Final BCVA correlated with baseline IS/OS interruption length.
Conclusions:
- Baseline BCVA, CRT, and IS/OS integrity are significant predictors of functional outcomes.
- These factors can help in counseling patients on expected results after macular pucker surgery.

