Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

25
Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
25
Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

1.6K
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
1.6K
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

885
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
885
Assessment of the Gastrointestinal System I: Subjective Data01:17

Assessment of the Gastrointestinal System I: Subjective Data

842
Assessing the gastrointestinal (GI) system is a complex process that begins with collecting subjective data. This data, collected through patient interviews, provides crucial insights into the patient's health history, perception patterns, and lifestyle habits, all contributing significantly to GI health.
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems...
842
Other Disorders of Digestive System01:30

Other Disorders of Digestive System

1.7K
The gastrointestinal tract is susceptible to various disorders. If the lower esophageal sphincter is damaged, stomach acid can flow back into the esophagus, causing irritation and inflammation of the lining. This condition is called gastroesophageal reflux disease (known as heartburn) and may cause chest pain and difficulty swallowing. In the stomach, prolonged use of nonsteroidal anti-inflammatory drugs like aspirin, chronic alcohol consumption, bacterial infections such as Helicobacter...
1.7K
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

1.9K
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
1.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of the clinical impact of different telemedicine practices in intensive care units: A stepped-wedge cluster randomized clinical trial (TELESCOPE 2): Study protocol.

Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine·2026
Same author

Contemporary validation of a SAPS 3 customized version in patients admitted to Brazilian and Uruguayan intensive care units: a multicenter cohort study.

Critical care science·2026
Same author

Using the SOFA 2.0 score: a quick guide for clinicians and researchers.

Critical care science·2025
Same author

The role of serum lactate and hypotension in mortality risk stratification for critically ill COVID-19 patients: insights from a large retrospective ICU cohort.

BMC infectious diseases·2025
Same author

Right ventricle and venous system: bridging physiology and clinical practice. A narrative review.

Critical care science·2025
Same author

Rationale and Methodological Approach Underlying the Development of the Sequential Organ Failure Assessment (SOFA)-2 Score: A Consensus Statement.

JAMA network open·2025

Related Experiment Video

Updated: Apr 22, 2026

Author Spotlight: Reliable and Reproducible In Vitro Assessment of Drug Impact on Rat Intestinal Tubes
06:01

Author Spotlight: Reliable and Reproducible In Vitro Assessment of Drug Impact on Rat Intestinal Tubes

Published on: July 26, 2024

1.0K

Prolonged gastrointestinal dysfunction in critically ill patients.

Suzana Margareth Lobo1, Amanda Lucia Diaz Miranda2

  • 1Faculdade de Medicina de Rio Preto, Hospital de Base, São Jose do Rio Preto, São Paulo, Brasil.

Revista Brasileira De Terapia Intensiva
|October 11, 2014
PubMed
Summary

Prolonged gastrointestinal dysfunction is common in critically ill patients, affecting 35% of those studied. High lactate and low oxygenation predict this condition, highlighting key risk factors for intensive care unit patients.

More Related Videos

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

21.4K

Related Experiment Videos

Last Updated: Apr 22, 2026

Author Spotlight: Reliable and Reproducible In Vitro Assessment of Drug Impact on Rat Intestinal Tubes
06:01

Author Spotlight: Reliable and Reproducible In Vitro Assessment of Drug Impact on Rat Intestinal Tubes

Published on: July 26, 2024

1.0K
Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
09:44

Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation

Published on: September 11, 2012

21.4K

Area of Science:

  • Critical Care Medicine
  • Gastroenterology
  • Intensive Care Unit Management

Background:

  • Prolonged gastrointestinal dysfunction is a significant complication in critically ill patients.
  • Understanding its prevalence and predictors is crucial for improving patient outcomes in the intensive care unit.

Purpose of the Study:

  • To determine the prevalence of prolonged gastrointestinal dysfunction in critically ill patients.
  • To identify independent predictors of this dysfunction in the intensive care unit setting.

Main Methods:

  • Retrospective observational cohort study of 128 intensive care unit patients with stays >4 days.
  • Daily assessment of gastrointestinal function based on physical exam and nutritional support.
  • Logistic regression analysis to identify predictive factors.

Main Results:

  • Prolonged gastrointestinal dysfunction occurred in 35% of patients, significantly higher in surgical (27%) vs. medical (8%) patients.
  • Higher prevalence of dysfunction observed in patients with moderate/severe edema (51%) vs. no edema (22.5%).
  • Admission serum lactate >5.2 mEq/L (RR 6.69) and low oxygenation index (RR 12.4) were significant predictors.

Conclusions:

  • Prolonged gastrointestinal dysfunction is highly prevalent in critically ill patients.
  • Admission serum lactate levels and low oxygenation index are independent predictors of prolonged gastrointestinal dysfunction.
  • These findings emphasize the importance of monitoring these parameters in intensive care unit patients.