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Optimizing ART adherence: update for HIV treatment and prevention
Reuben N Robbins1, Anya Y Spector, Claude A Mellins
1HIV Center for Clinical and Behavioral Studies, New York State Psychiatric Institute and Columbia University, 1051 Riverside Drive #15, New York, NY, 10032, USA, rnr2110@columbia.edu.
Achieving optimal adherence to antiretroviral therapy (ART) is crucial for HIV treatment and prevention. This review covers recent ART adherence interventions from 2013 onwards, updating previous literature.
Area of Science:
- Infectious Diseases
- Public Health
- Pharmacology
Background:
- Optimal adherence to antiretroviral therapy (ART) is essential for viral suppression and improved health outcomes in individuals with HIV.
- ART adherence serves as both a treatment and prevention strategy, reducing HIV transmission risk.
- Long-term adherence to ART presents significant challenges for patients and healthcare providers.
Purpose of the Study:
- To review and synthesize recent advancements in antiretroviral therapy (ART) adherence interventions.
- To update the literature on ART adherence strategies beyond 2012.
- To inform clinicians and researchers about current developments in HIV treatment and prevention adherence.
Main Methods:
- Systematic review of peer-reviewed journal articles and conference abstracts.
- Literature search focused on ART adherence interventions published from 2013 to the present.
- Inclusion of studies addressing various aspects of ART adherence.
Main Results:
- Identified numerous ART adherence interventions developed and tested between 2013 and the present.
- Highlighted emerging trends and novel strategies in ART adherence.
- Provided an updated overview of the evidence base for ART adherence interventions.
Conclusions:
- Continued development and evaluation of ART adherence interventions are critical.
- Emerging biomedical approaches and pre-exposure prophylaxis (PrEP) guidelines necessitate updated adherence strategies.
- Effective ART adherence interventions are key to maximizing treatment efficacy and preventing HIV transmission.
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