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Updated: Apr 22, 2026
Synthesis of Core-shell Lanthanide-doped Upconversion Nanocrystals for Cellular Applications
Published on: November 10, 2017
Interactions of CT DNA with hexagonal NaYF4 co-doped with Yb(3+)/Tm(3+) upconversion particles
Xiuxue Yuan1, Wenchao Gu1, Mengsi Xiao1
1College of Chemistry and Materials Science, Analysis and Testing Centre, Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials, Key Laboratory of Applied Photochemistry, Nanjing Normal University, China.
Abstract:
The interaction of UCPs with CT DNA are studied in detail by zeta potential, Energy dispersive spectrometer (EDS) spectroscopy, Thermogravimetric (TGA) analysis, DNA melting determination and various spectroscopic techniques including Ultraviolet-Visible (UV-Vis) absorption, fluorescence, circular dichroism (CD), Fourier transform infrared (FTIR) and Raman spectroscopy. The results indicate that CT DNA can assemble on the surface of UCPs mainly by relative stronger hydrophobic force and electrostatic binding, and the predominant interaction site is the deoxyribosyl phosphate backbone of CT DNA. Moreover, after interacting with UCPs, the double helix structure of DNA is undamaged.
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